Master's/Doctoral Program in Life Science Innovation

Tetsuya Sakurai iD TRIOS researchmap

Director HP
Center for Artificial Intelligence Research,
University of Tsukuba

Professor, Institute of Systems and Information Engineering,
University of Tsukuba

1. Mathematical methods for data analysis
2. High performance algorithms on large-scale scientific simulations
3. Eigenvalue analysis

Selected Publications:

1. “Distributed collaborative feature selection based on intermediate representation”, Proceedings of the 28th International Joint Conference on Artificial Intelligence (IJCAI-19) 2019, 4142-4149.
2. “Complex moment-based supervised eigenmap for dimensionality reduction”, Proceedings of the Thirty-Third AAAI Conference on Artificial Intelligence (AAAI-19) 2019, 3910-3918.
3. “Spectral feature scaling method for supervised dimensionality reduction”, Proceedings of the 27th International Joint Conference on Artificial Intelligence (IJCAI-18) 2018, 2560-2566.

Hotaka Takizawa iD TRIOS researchmap

Professor HP
Institute of Systems and Information Engineering University of Tsukuba

Director
Academic Computing and Communications Center, University of Tsukuba

Ken Aoshima iD

Data & AI Lead,
Microbes & Host Defense Domain, DHBL,
Eisai Co., Ltd.

Professor, School of Integrative and Global Majors,
University of Tsukuba

Itoshi Nikaido iD researchmap

Team Leader HP
Laboratory for Bioinformatics Research,
RIKEN Center for Biosystems Dynamics Research

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. A development of novel bioinformatics techniques for genome science

Selected Publications:

1. “CellFishing.jl: an ultrafast and scalable cell search method for single-cell RNA sequencing”, Genome Biology 2019, 20 (1), 31.
2. “Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads”, Genome Biology 2018, 19 (1), 29.
3. “Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs”, Nature Communications 2018, 9 (1), 619.

Hiroshi Masuya iD researchmap

Head HP
Integrated Bioresource Information Division,
RIKEN BioResource Research Center

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Data integration and standardization of bioresource-related information
2. Development of homepage contents for communication tool for bioresource-related information
3. Development of methodology of the big-data analysis and data visualization

Selected Publications:

1. “An atlas of evidence-based phenotypic associations across the mouse phenome.”, Sci. Rep. 2020, 10, 3957.
2. “RIKEN MetaDatabase: A Database Platform for Health Care and Life Sciences as a Microcosm of Linked Open Data Cloud.”, Int. J. Semantic Web Inf. Syst. 2018, 14(1), 140-164.
3. “Identification of genetic elements in metabolism by high-throughput mouse phenotyping.”, Nat. Commun. 2018, 9, 288.

Tsuyoshi Miyazaki iD researchmap

Group Leader/MANA Principal Investigator HP
Research Center for Materials Nanoarchitectonics (MANA)
NIMS

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. First-principles calculation
2. Molecular simulation
3. Computational Materials Science

Selected Publications:

1. “Efficient Calculation of Electronic Structure Using O(N) Density Functional Theory”, Journal of Chemical Theory and Computation 2017, 13 (9), 4146-4153.
2. “Density-functional theory study of gramicidin A ion channel geometry and electronic properties”, Journal of The Royal Society Interface 2013, 10 (89), 20130547.
3. “O(N) methods in electronic structure calculations”, Reports on Progress in Physics 2012, 75 (3), 036503.

Yasunori Futamura iD TRIOS researchmap

Associate Professor
Institute of Systems and Information Engineering, University of Tsukuba

Ye Xiucai iD TRIOS researchmap

Associate Professor
Institute of Systems and Information Engineering, University of Tsukuba

Dai Hai Nguyen iD TRIOS researchmap

Course Coordinator of T-LSI (Bioinformatics Course)

Assistant Professor HP
Institute of Systems and Information Engineering, University of Tsukuba

Hiroko Isoda iD TRIOS researchmap

Professor HP
Institute of Life and Environmental Sciences, University of Tsukuba

Kenichi Kashiwagi iD TRIOS researchmap

Professor HP
Institute of Humanities and Social Sciences, University of Tsukuba

1. Mechanism of productivity and technological progress in agro-food industry
2. Analysis on development of agro-food clusters based on promotion of local industries
3. Analysis on innovative agro-food value chain

Selected Publications:

1. “Technical Efficiency of Olive-growing Farms in the Northern West Bank of Palestine”, Sustainable Agriculture Research 2017, 6(1), 125-140.
2. “Technical efficiency of olive oil firms under the industrial upgrading programme in Tunisia”, New Medit: A Mediterranean Journal of Economics, Agriculture and Environment 2016, 15(4), 10-20.
3. “Productivity Growth and Technological Progress in the Palestinian Economy: Empirical Evidence from the West Bank”, Advances in Management & Applied Economics 2016, 6(1), 69-88.

Akifumi Ikehata iD researchmap

Group leader HP
Analytical Evaluation Group, Institute of Food Research, National Agriculture and Food Research Organization, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Development of data-driven science by integrating nondestructive spectroscopy and multi-omics
2. Development of non-invasive bio-spectroscopic analysis methods
3. Application of spectroscopic methods to food analysis

Selected Publications:

1. “The relationship between perceived freshness and water content of cabbage leaves: A near infrared imaging survey of substance distribution underlying product appearance”, LWT 2021, 139, 110523.
2. “An examination of the principle of non-destructive flesh firmness measurement of peach fruit by using VIS-NIR spectroscopy”, Heliyon 2018, 4(2), e00531.
3. “Identification of informative bands in the short-wavelength NIR region for non-invasive blood glucose measurement “, Biomedical Optics Express 2016, 7 (7), 2729-2737.

Susumu Kawasaki researchmap

Senior Researcher HP
Food Research Institute, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

Isao Kobayashi iD researchmap

Principal Researcher HP
Food Research Institute, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

Masatomo Kobayashi iD researchmap

Head HP
Experimental Plant Division, RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Shinya Takahashi iD TRIOS researchmap

Associate Professor, Institute of Life and Environmental Sciences, University of Tsukuba

Marcos Antonio Das NEVES iD TRIOS

Associate Professor researchmap 
Institute of Life and Environmental Sciences, University of Tsukuba

1. Food nanotechnology
2. Development of functional foods
3. Food emulsions as bioactives delivery systems

Selected Publications:

1. “Assessment of Oxidative Stability in Fish Oil-in-Water Emulsions: Effect of Emulsification Process, Droplet Size and Storage Temperature”, Journal of Food Process Engineering 2015, 40 (1), e12316.
2. “Antimicrobial Oil-in-Water Nanoemulsions: Synergistic Effect of Nisin and Carvacrol against Bacillus subtilis”, Journal of Food Science and Engineering 2016, 6 (2), 63-74.
3. “Development of novel bioactives delivery systems by micro/nanotechnology”, Current Opinion in Food Science 2015, 1, 7-12.

Yuko Kusakabe iD researchmap

Deputy Leader HP
Food Research Institute, NARO

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Research on the receptor mechanisms of taste and oral sensations
2. Research on physiological responses to oral sensation
3. Research on the sensory fluctuations during feeding

elected Publications:

1. “Distinct Human and Mouse Membrane Trafficking Systems for Sweet Taste Receptors T1r2 and T1r3;, PLOS ONE 2014, 9 (7), e100425.
2. “Evaluation of Taste Solutions with or without Aromas Based on the Relationship between Individual Resting and Stimulated Salivation”, Food Science and Technology Research 2020, 26(3), 451-457.
3. “Relationships between the response of the sweet taste receptor, salivation toward sweeteners, and sweetness intensity”, Food Science & Nutrition 2021, 9 (2), 719-727.

Satoshi Fukumitsu

Team Manager, Innovation center,NIPPN CORPORATION 

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Farhana Ferdousi iD TRIOS researchmap

Course Coordinator of T-LSI (Food Innovation Course)

Assistant Professor, Institute of Life and Environmental Sciences, University of Tsukuba

Iwane Suzuki iD TRIOS researchmap

Professor HP
Institute of Life and Environmental Sciences, University of Tsukuba

1. Interaction of carbon and nitrogen metabolism in microalgae
2. Mechanisms for acclimation to environmental conditions of photosynthetic activity
3. Biochemical and molecular biological studies in biomass production in microalgae

Selected Publications:

1. “Cold-regulated genes under control of the cold sensor Hik33 in Synechocystis”, Molecular Microbiology 2001, 40 (1), 235-244.
2. “The pathway for perception and transduction of low-temperature signals in Synechocystis”, The EMBO Journal 2000, 19 (6), 1327-1334.
3. “Genetic engineering of the unsaturation of fatty acids in membrane lipids alters the tolerance of Synechocystis to salt stress”, Proceedings of the National Academy of Sciences 1999, 96 (10), 5862-5867.

Kenji Tamura iD TRIOS researchmap

Professor HP
Institute of Life and Environmental Sciences, University of Tsukuba

1. Analysis of soil microelements
2. Mechanism of High quality soils

Selected Publications:

1. “Interregional traceability of Tunisian olive oils to the provenance soil by multielemental fingerprinting and chemometrics”, Food Chemistry 2019, 283, 656-664.
2. “Six-year monitoring of the vertical distribution of radiocesium in three forest soils after the Fukushima Dai-ichi Nuclear Power Plant accident”, Journal of Environmental Radioactivity 2018, 192, 172-180.
3. “Physiological and Psychological Effects of Scent of Soil on Human Beings”, Open Journal of Soil Science 2017, 07 (09), 235-244.

Mitsuko Aono iD researchmap

Deputy director HP
Biodiversity Division, NIES

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Molecular-biological studies on effect of tropospheric ozone and other stress factors on plants in global environmental changes
2. Dynamics of genetically-modified crops in the wild

Selected Publications:

1. “Ozone-Sensitive Arabidopsis Mutants with Deficiencies in Photorespiratory Enzymes”, Plant and Cell Physiology 2017, 58 (5), 914-924.
2. “Seeds of a Possible Natural Hybrid between Herbicide-Resistant Brassica napus and Brassica rapa Detected on a Riverbank in Japan”, GM Crops 2011, 2 (3), 201-210.
3. “Disruption of a Gene Encoding C4-Dicarboxylate Transporter-Like Protein Increases Ozone Sensitivity Through Deregulation of the Stomatal Response in Arabidopsis thaliana”, Plant and Cell Physiology 2008, 49 (1), 2-10.

Moriya Ohkuma researchmap

Head HP
Microbe Division (Japan Collection of Microorganisms),
RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Genomics and bioresources of yet-uncultured microbial diversity
2. Molecular microbial ecology of microbial symbionts
3. Taxonomy and systematics of diverse microorganisms

Selected Publications:

1. “Isolation and characterization of a thermophilic sulfur- and iron-reducing thaumarchaeote from a terrestrial acidic hot spring”, The ISME Journal, 2019, 13 (10), 2465–2474.
2. “Lactococcus reticulitermitis sp. nov., isolated from the gut of the subterranean termite Reticulitermes speratus”, International Journal of Systematic and Evolutionary Microbiology 2018, 68 (2), 596-601.
3. “Acetogenesis from H2plus CO2and nitrogen fixation by an endosymbiotic spirochete of a termite-gut cellulolytic protist”, Proceedings of the National Academy of Sciences 2015, 112 (33), 10224-10230.

Yoshihito Ohmura iD researchmap

Head of the Division HP
Division of Fungi and Algae, Department of Botany,
National Museum of Nature and Science

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Lichen biodiversity in Japan and the related regions of As
2. Relationship between lichens and changes in the atmospheric environment
3. Evolutionary relationship between mycobiont and photobiont in lichens

Selected Publications:

1. “Contribution to the Knowledge of the Lichen Mycota of Myanmar (I) Twenty Species Newly Recorded from Southern Myanmar”, Taiwania 2020,65(4), 548-558.
2. “137Cs concentrations in foliose lichens within Tsukuba-city as a reflection of radioactive fallout from the Fukushima Dai-ichi Nuclear Power Plant accident”, Journal of Environmental Radioactivity 2015, 141, 38-43.
3. “Photobiont diversity within populations of a vegetatively reproducing lichen, Parmotrema tinctorum, can be generated by photobiont switching”, Symbiosis 2019, 77, 59-72.

Noriaki Kawano researchmap

Section head HP
Breeding and Physiology Laboratory
Tsukuba Division, Research Center for Medicinal Plant Resources, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Masanori Kikuchi iD researchmap

Group leader HP
Bioceramics Group, Research Center for Macromolecules and Biomaterials, NIMS

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Ceramics in medicine
2. Application of bio-derived minerals
3. Biomimetic materials

Selected Publications:

1. “Preparation of anti-decay self-setting pastes of hydroxyapatite/collagen utilizing (3-glycidoxypropyl)trimethoxysilane”, Journal of Asian Ceramic Societies 2018, 6 (4), 322-331.
2. “Reactivity Improvement of Dicalcium Phosphate Dihydrate with Fluoride for Its Removal from Waste and Drinking Water”, Universal Journal of Materials Science 2016, 4 (3), 60-64.
3. “Self-organization mechanism in a bone-like hydroxyapatite/collagen nanocomposite synthesized in vitro and its biological reaction in vivo”, Biomaterials 2001, 22 (13), 1705-1711.

Masatomo Kobayashi iD researchmap

Head HP
Experimental Plant Division,
RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Tomoya Tsuji iD

Professor HP
Malaysia-Japan International Institute of Technology (MJIIT), Universiti Teknologi Malaysia

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Phase Equilibrium for the system containing spray propellant
2. Measurement and prefiction of solubility of inorganic gases in organic compounds
3. Therimophysical properties of dimethyl ether

Selected Publications:

1. “Measurement and prediction of bubble point pressure of a novel solvent with propellant for color spray”, Fluid Phase Equilibria 2020, 505, 112366.
2. “Gas solubilities of nitrogen or oxygen in benzene, divinylbenzene, styrene and of an equimolar (N2:O2) mixture in styrene at (293–313) K”, Fluid Phase Equilibria , 2019, 492, 34-40.
3. “SO2 Solubility in Low Molecular Weight Polyethylene Glycol Dimethyl Ether and Correlation using Cubic Equation of State”, Journal of Solution Chemistry 2019, 48, 1035-1045.

Masanori NakaeiD researchmap

Senior Curator HP
Division of Vertebrates,
Department of Zoology, National Museum of Nature and Science

Professor, School of Integrative and Global Majors,
University of Tsukuba

Kayo Yoshimatsu researchmap

Director HP
Research Center for Medicinal Plant Resources, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Sosaku Ichikawa iD TRIOS researchmap

Professor
Institute of Life and Environmental Sciences, University of Tsukuba

1. Development and characterization of emulsion-based carrier systems
2. Development and characterization of liposome-based carrier systems
3. Development of new nano-/micro- carrier systems for efficient delivery of bioactive

Selected Publications:

1. “Freeze-dryable lipid vesicles with size tunability and high encapsulation efficiency prepared by the multiple emulsification-solvent evaporation method”, Colloids and Surfaces B: Biointerfaces 2017, 159, 412-418.
2. “Mixing characterization of liquid contents in human gastric digestion simulator equipped with gastric secretion and emptying”, Biochemical Engineering Journal 2017, 122, 85-90.
3. “Development and Fundamental Characteristics of a Human Gastric Digestion Simulator for Analysis of Food Disintegration”, Japan Agricultural Research Quarterly: JARQ 2017, 51 (1), 17-25.

Tsunenori Kameda iD researchmap

Group Leader HP
Silk Materials Research Group,
Institute of Agrobiological Sciences, NARO

Professor , School of Integrative and Global Majors,
University of Tsukuba

1. Fundamental research on relation between the structure and properties of silk proteins
2. Development of various fabrication processes for formation of innovative silk materials with different characteristics
3. Commercialize the various unutilized silk produced by insects other than silkworm as new material.

Selected Publications:

1. “A study of the extraordinarily strong and tough silk produced by bagworms”, Nature Communications 2019, 10 (1), 1469.
2. “Transdermal delivery of 40-nm silk fibroin nanoparticles”, Colloids and Surfaces B: Biointerfaces 2019, 175, 564-568.
3. “Genome Editing Advances the Structural Study of Silk”, ACS Biomaterials Science & Engineering 2018, 4 (3), 832-835.

Shinji Sugiura iD researchmap

Chief Senior Researcher HP
Drug Assay Device Research Group,
Biotechnology Research Institute for Drug Discovery, AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Organs-on-a-chip for drug discovery
2. Engineering the micro-scale cell culture environment
3. Micro-scale cell process engineering with functional materials

Selected Publications:

1. “A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform”, Lab on a Chip 2018, 18 (1), 115-125.
2. “Morphology-based optical separation of subpopulations from a heterogeneous murine breast cancer cell line”, PLOS ONE 2017, 12 (6), e0179372.
3. “Click-crosslinkable and photodegradable gelatin hydrogels for cytocompatible optical cell manipulation in natural environment”, Scientific Reports 2015, 5 (1), 15060.

Kimio Sumaru iD researchmap

Group Leader HP
Cellular and Molecular Biotechnology Research Institute,
AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Bio-application of Photo-responsive Functional Polymer Materials
2. Cell Culture systems to Bring out Physiological Functions
3. On-plate Cell Manipulation Technolog

Selected Publications:

1. “Photolithographic Fabrication of Semi 3-D Microstructures Composed of Flexible Hydrogel Sheet for in Vivo-like Cell Culture System”, ACS Applied Bio Materials 2019, 2 (10), 4129-4133.
2. “Automated Adherent Cell Elimination by a High-Speed 1 Laser Mediated by a Light-Responsive Polymer”, Communications Biology 2018, 1-218, 1-9.
3. “Photoresponsive Aqueous Dissolution of Poly(N-Isopropylacrylamide) Functionalized with o-Nitrobenzaldehyde through Phase Transition”, Biomacromolecules 2018, 19, 2913-2922.

Yuji Teramura iD researchmap

Chief Senior Researcher HP
Cellular and Molecular Biotechnology Research Institute(CMB),
AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Biomaterials for cell and organ transplantation
2. Polymer materials for cell and endothelium modification
3. Materials for manipulation of cells and exosomes in vitro and in vivo

Selected Publications:

1. “Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation”, Advanced Functional Materials 2021, 31, 2008167.
2. “Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications”, Langmuir 2020, 36, 41, 12088–12106.
3. “Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine”, Regenerative Therapy 2021, 18, 408-417.

Hidetoshi Teramoto iD researchmap

Deputy Leader HP
Silk Materials Research Group,
Division of Silk-Producing Insect Biotechnology, Institute of Agrobiological Sciences, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Genetic code expansion of silkworm
2. Development and application of silk materials incorporated with synthetic amino acids
3. Application of high molecular weight silk sericin

Selected Publications:

1. “Characterization and Scaled-Up Production of Azido-Functionalized Silk Fiber Produced by Transgenic Silkworms with an Expanded Genetic Code”, International Journal of Molecular Sciences 2019, 20 (3), 616.
2. “Genetic Code Expansion of the Silkworm Bombyx mori to Functionalize Silk Fiber”, ACS Synthetic Biology 2018, 7 (3), 801-806.
3. “Azide-Incorporated Clickable Silk Fibroin Materials with the Ability to Photopattern”, ACS Biomaterials Science & Engineering 2016, 2 (2), 251-258.

Shuichiro Tomita iD researchmap

Leader HP
New Silk Research Unit,
Division of Biotechnology, Institute of Agrobiological Sciences, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Evolution and development of insect appendages
2. Physiology of post embryonic development of insect
3. Molecular mechanisms of appendage regeneration

Selected Publications:

1. “BHR4 nuclear receptor coordinates the timing of pupal ecdysis through ecdysteroid biosynthesis in Bombyx mori”, Journal of Insect Biotechnology and Sericology 2012, 81 (2-3), 45-53.
2. “Exploring the molecular phylogeny of phasmids with whole mitochondrial genome sequences”, Molecular Phylogenetics and Evolution 2011, 58 (1), 43-52.
3. “Abd-B suppresses lepidopteran proleg development in posterior abdomen”, Developmental Biology 2009, 328 (2), 403-409.

Shunsuke Tomita iD researchmap

Chief Senior Researcher HP
Nano-biodevice Research Group,
Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Development of bioanalytical techniques termed ‘chemical tongue,’ integrating fluorescent molecular arrays and machine learning.
2. Exploration of potential applications for the chemical tongue, targeting various bioanalytes.
3. Elucidation of the mechanisms of liquid-liquid phase separation (LLPS) driven by biopolymers.

Selected Publications:

1. “Polymer-based chemical-nose systems for optical-pattern recognition of gut microbiota”, Chemical Science 2022, 13, 5830-5837.
2. “A polymer-based chemical tongue for the non-invasive monitoring of osteogenic stem-cell differentiation by pattern recognition of serum-supplemented spent media”, Journal of Materials Chemistry B 2022, 58, 11083-11086.
3. “Quadruplex folding of DNA promotes the condensation of linker histones via liquid-liquid phase separation”, Journal of the American Chemical Society 2021, 143, 9849-9857.

Hidehiko Hirakawa iD TRIOS researchmap

Course Coordinator of T-LSI (Biomolecular Engineering Course)

Associate Professor HP
Institute of Life and Environmental Sciences,
University of Tsukuba

1. Selective protein assembly
2. Engineering of cytochrome P450
3. Enzyme immobilization

Selected Publications:

1. “Immobilization of a Bacterial Cytochrome P450 Monooxygenase System on a Solid Support”, Angew. Chem. Int. Ed. 2016, 55 (48), 15002-15006.
2. “Supramolecular protein assembly supports immobilization of a cytochrome P450 monooxygenase system as water-insoluble gel”, Sci. Rep. 2015, 5 (1), 8648.
3. “Ca 2+ -independent sortase-A exhibits high selective protein ligation activity in the cytoplasm of Escherichia coli ”, Biotechnol. J. 2015, 10 (9), 1487-1492.

Masashi Yanagisawa iD TRIOS researchmap

Director and Professor HP
International Institute for Integrative Sleep Medicine, University of Tsukuba

1. Large-scale, forward genetic screening of genes responsible for sleep/wake regulation in mice
2. Discovery and medicinal chemistry of novel drugs for sleep disorders
3. Visualizing and manipulating the activity of neurons involved in sleep/wake regulation

Selected Publications:

1. “Quantitative phosphoproteomic analysis of the molecular substrates of sleep need”, Nature 2018, 558 (7710), 435-439.
2. “Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models”, Proceedings of the National Academy of Sciences of the United States of America 2017, 114 (22), 5731-5736.
3. “Forward-genetics analysis of sleep in randomly mutagenized mice”, Nature 2016, 539 (7629), 378-383.

Shinji Saiki iD TRIOS researchmap

Professor HP
Institute of Medicine, University of Tsukuba

Yasuyuki KidaiD researchmap

Group leader HP Cellular and Molecular Biotechnology Research Institute
Stem Cell Biotechnology Research Group
National Institute of Advanced Industrial Science and Technology

Professor, School of Integrative and Global Majors
University of Tsukuba

1. Developing technology for the reconstruction of in vitro organ networks using human pluripotent stem cells.
2. Elucidation of the metabolism mechanisms of cancer to overcome the intractability of solid tumours.
3. Development of pivotal technologies for disease research and the discovery of medicines using stem cells.

Selected Publications:

1. “Selective Induction of Human Autonomic Neurons Enables Precise Control of Cardiomyocyte Beating”, Scientific Reports 2020, 10, 9464.
2. “Adipose-derived mesenchymal stem cells differentiate into heterogeneous cancer-associated fibroblasts in a stroma-rich xenograft model”, Scientific Reports 2021, 11, 4690.
3. “Fabrication of Perfusable Vascular Channels and Capillaries in 3D Liver-like Tissue”, Scientific Reports 2020, 10, 5646.

Atsushi KunoiD researchmap

Research Group leader HP Cellular and Molecular Biotechnology Research Institute
Molecular ＆Cellular Glycoproteomics Research Group
AIST

Professor, School of Integrative and Global Majors
University of Tsukuba

1. Glyco-biomarker/glyco-target R&D
2. Glyco-DB construction including LM-GlycomeAtlas
3. System development for full-automatic glycan profiling

Selected Publications:

1. “Discovery of pancreatic ductal adenocarcinoma-related aberrant glycosylations: a multilateral approach of lectin microarray-based tissue glycomic profiling with public transcriptomic datasets”, Frontiers in Oncology 2020, 10, 338.
2. “LM-GlycomeAtlas Ver. 2.0: An integrated visualization for lectin microarray-based mouse tissue glycome mapping data with lectin histochemistry”, J Proteome Res 2021, 20, 2069-2075.
3. “Lectin bead array in a single tip facilitates fully automatic glycoprotein profiling”, Scientific Reports 2019, 191 11162-11169.

Yoshihiro Miwa iD researchmap

Organizer HP
Gene Engineering Division, RIKEN BioResource Research Center

Professor, School of Integrative and Global Majors, University of Tsukuba

1. Non-invasive NIR live imaging of disease model mice
2. Analyses of fibrosis and 3D tissue formation by collagen live imaging

Selected Publications:

1. “A Novel iRFP-Incorporated in vivo Murine Atherosclerosis Imaging System”, Scientific Reports 2018, 8, 14515.
2. “Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice”, Scientific Reports 2017, 46597.
3. “In Vivo image Analysis Using iRFP Transgenic Mice”, Experimental Animals 2014, 63(3), 311-319.

Yasuhiro Yasutomi researchmap

Director HP
Tsukuba Primate Research Center, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Atsushi Yoshiki iD researchmap

Head HP
Experimental Animal Division, RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Collection, preservation, quality-control and distribution of mouse resources
2. Research and development for quality control of mouse resources
3. Development of novel tools for gene functions and mouse models for human diseases

Selected Publications:

1. “Off- and on-target effects of genome editing in mouse embryos”, Journal of Reproduction and Development 2019, 65 (1), 1-5.
2. “Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality”, Neurobiology of Disease 2016, 96, 271-283.
3. “High-throughput discovery of novel developmental phenotypes”, Nature 2016, 537, 508–514.

Haruka Ozaki iD TRIOS researchmap

Associate Professor HP
Institute of Medicine, University of Tsukuba

1. Predication of functions pf genomic sequences and cells
2. Automation of life science research
3. Medical data analysis

Selected Publications:

1. “Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs”, Nature Communications 2018, 9, 619.
2. “SAGAS: Simulated annealing and greedy algorithm scheduler for laboratory automation”, SLAS Technology 2023, 19:34.
3. “Cell-to-cell interaction analysis of prognostic ligand-receptor pairs in human pancreatic ductal adenocarcinoma”, Biochem Biophys Rep. 2021, 28:101126.

Kazuko Tajiri　 iD researchmap

Chief HP
Department of Cardiology
National Cancer Center Hospital East

Associate Professor, School of Integrative and Global Majors
University of Tsukuba

Dong-Zhu Xu iD TRIOS researchmap

Course Coordinator of T-LSI (Disease Mechanism Course)

Associate Professor
Institute of Medicine, University of Tsukuba