Student Achievements

Awards received by students

11/11/2021

Atsushi Tsuyukubo(露久保 淳), Doctoral course student in Drug Discovery(創薬開発領域 博士後期課程所属)
Supervisor: Prof. Toshiyuki Kanamori(金森 敏幸 教授)

坂垣宏学生奨励賞

The award was presneted to the student for his presentation at ”The 34th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments” on November 11-13, 2021, OIST, Okinawa, Japan.

A brief overview

「やわらかな自立浮遊ハイドロゲル膜上でのスフェロイド培養による肝特異的機能発現」
"Expression of liver-specific functions by spheroid culture on flexible floating hydrogel membrane"

露久保 淳1,2、須丸 公雄2、森下 加奈2、金森 敏幸1,2
Atsushi Tsuyukubo1,2, Kimio Sumaru2, Kana Morishita2, Toshiyuki Kanamori1,2
(1 筑波大院グローバル、2 産総研細胞分子工学)
1 SIGMA, Univ. of Tsukuba, 2 CMB, AIST

医薬品開発における動物試験代替法として、ヒト培養細胞を用いた評価(細胞アッセイ)が注目されている。生体外で細胞の臓器特異的機能を発現させることを目指して我々は、培地中で自立的に浮遊するハイドロゲル膜を細胞の培養足場として用いたスフェロイド培養系を構築した。基材に固定された培養と比較して本培養系では、細胞のグルコース消費量に対する乳酸産生量の減少が確認され、好気的な培養環境が構築されていることが示唆された。さらに、薬物代謝酵素CYP1A2に関する遺伝子発現量の向上が確認され、本培養系はHepG2の肝特異的機能の発現に寄与することが示唆された。
As one of the alternatives to animal experiments in the drug development, bioassay using cultured human cells (cell-based assay) has been gaining increased attention. Aiming to express organ-specific functions of cells in vitro, we constructed cell spheroid culture system using flexible hydrogel membrane floating in the culture medium as cell culture scaffold. Compared to the cell culture system immobilized on the substrate, lactate production against glucose consumption decreased, and it was suggested that aerobic culture environment was constructed on the floating membrane. Moreover, gene expression level of CYP1A2, which is one of the drug-metabolizing enzymes, was enhanced, and this result suggests that the spheroid culture system on the floating hydrogel membrane expressed liver-specific functions of HepG2 cells.

09/02/2021

Anissa Nofita Sari, Doctoral course student in Disease Mechanism
Supervisor: Prof. Renu Wadhwa KAUL

Graduate Student Presentation Award

The award was preseneted to the student for her presentation at he 93rd Annual Meeting, Japanese Tissue Culture Association. This conference was held during September 1-2, 2021 at Hiroshima, Japan.

31/08/2021


Jane Chizie Ogbonna, Master's course student in Food Innovation
Supervisor: Dr. Marcos Antonio NEVES

Outstanding Presentation Award

The award was presneted to the student for their presentation at our 4th TLSI Student Workshop organized on August 31, 2021 "Online".

31/08/2021


Moena Ishikawa, Master's course student in Disease Mechanism
Supervisor: Dr. Katsutaka OHISHI


Outstanding Presentation Award

The award was presneted to the student for their presentation at our 4th TLSI Student Workshop organized on August 31, 2021 "Online".

31/08/2021


Yunong Jiang, Master's course student in Drug Discovery
Supervisor: Dr. Naohiro NODA

Outstanding Presentation Award

The award was presneted to the student for their presentation at our 4th TLSI Student Workshop organized on August 31, 2021 "Online".

24/02/2021

Munguti Peter Muindi, Master's course student in Drug Discovery
Supervisor: Prof. Tsunenori Kameda

Outstanding Presentation Award

The award was presneted to the student for his presentation at our 3rd TLSI Student Workshop organized on Febrary 24, 2021 "Online".

24/02/2021

Yuki Utsugi, Master's course student in Drug Discovery
Supervisor: Associate Prof. Yusaku Miyamae

Outstanding Presentation Award

The award was presneted to the student for his presentation at our 3rd TLSI Student Workshop organized on Febrary 24, 2021 "Online".

22/1/2021

Atsushi Tsuyukubo(露久保 淳), Doctoral course student in Drug Discovery(創薬開発領域 博士後期課程所属)
Supervisor: Prof. Toshiyuki Kanamori(金森 敏幸 教授)

Soft Matter Poster Prize

The award was presneted to the student for his presentation at ”The 32nd Society of Polymer Science, Japan-Research Group on Polymer Gels Symposium” on January 21-22, 2021 online.

A brief overview

「やわらかな自立浮遊ハイドロゲル膜上での新たな細胞培養」
"Novel cell culture system on flexible hydrogel membrane floating in the culture medium"

露久保 淳1,2、須丸 公雄2、森下 加奈2、金森 敏幸1,2
Atsushi Tsuyukubo1,2, Kimio Sumaru2, Kana Morishita2, Toshiyuki Kanamori1,2
(1 筑波大院グローバル、2 産総研細胞分子工学)
1 SIGMA, Univ. of Tsukuba, 2 CMB, AIST

一部が基材に固定されたまま培養液中で自立的に浮遊するやわらかなハイドロゲル膜を足場とする細胞集塊(スフェロイド)培養系を構築した。本培養系でHepG2を培養したところ、従来の基材に固定された単層培養と比較して、肝特異的な薬物代謝酵素に関する遺伝子発現量の向上が確認された。
We constructed cell spheroid culture system using flexible hydrogel membrane floating in the culture medium as cell culture scaffold. When HepG2 cells were incubated in this culture system, it was shown that gene expression of the liver specific drug metabolizing enzyme was enhanced compared to conventional monolayer cell culture system on the substrate.

13/11/2020

Atsushi Tsuyukubo(露久保 淳), Doctoral course student in Drug Discovery(創薬開発領域 博士後期課程所属)
Supervisor: Prof. Toshiyuki Kanamori(金森 敏幸 教授)

Student Award(学生賞)

The award was presneted to the student for his presentation at ”Symposium on Membrane 2020(膜シンポジウム2020)”(Symposium presented by the Membrane Society of Japan) on November 12-13, 2020 online.

A brief overview

「細胞機能の発現を目指した自立浮遊ハイドロゲル膜足場の創製」
"Development of cell culture scaffold composed of floating hydrogel membrane for expression of physiological cell functions"

露久保淳1,2、須丸公雄2、森下加奈2、金森敏幸1,2
Atsushi Tsuyukubo1,2, Kimio Sumaru2, Kana Morishita2, Toshiyuki Kanamori1,2
(1 筑波大院グローバル、2 産総研細胞分子工学)
1 SIGMA, Univ. of Tsukuba, 2 CMB, AIST

従来のディッシュ培養では大幅に抑制される細胞機能の発現を目指して、一部が基材に固定されたまま培地中で自立的に浮遊するやわらかな細胞接着性ハイドロゲル膜を創製し、このゲル膜を培養足場とする新規細胞培養系を開発した。
Aiming at expression of physiological cell functions which are suppressed drastically in the conventional dish cell culture, we developed a novel cell culture system using flexible cell-adhesive hydrogel membrane floating in the culture medium as cell culture scaffold.

26/02/2020

Khai Wenn Seah, Master's course student in Food Innovation
Supervisor: Prof. Marcos Antonio Das NEVES

Outstanding Presentation Award

The award was presneted to the student for her presentation at our 2nd TLSI Student Workshop organized on Febrary 26, 2020 at University of Tsukuba, Tsukuba, Japan.

26/02/2020

Yoshiaki Uchida, Master's course student in Food Innovation
Supervisor: Prof. Hiroko Isoda

Outstanding Presentation Award

The award was presneted to the student for her presentation at our 2nd TLSI Student Workshop organized on Febrary 26, 2020 at University of Tsukuba, Tsukuba, Japan.

12/2019

Yoshiaki UCHIDA, Master's course student in Food Innovation
Supervisor: Prof. Hiroko Isoda

Best Poster Award

The award was presneted to the student for her presentation at 15th TUNISIA-JAPAN SYMPOSIUM ON SCIENCE, SOCIETY AND TECHNOLOGY (TJASST2019).

9/10/2019

Atsushi TSUYUKUBO, Doctoral course student in Drug Discovery
Supervisor: Prof. Toshiyuki Kanamori

Poster Award

The award was presneted to the student for her presentation at the 68th Symposium on Macromolecules.

02/09/2019

Khai Wenn Seah, Master's course student in Food Innovation
Supervisor: Prof. Marcos Antonio Das NEVES

Outstanding Presentation Award

The award was presneted to the student for her presentation at our 1st TLSI Student Workshop organized on September 2, 2019 at University of Tsukuba, Tsukuba, Japan.

     

"Preparation and characterization of highly concentrated monodisperse oil-in water(O/W)emulsion using microchannel emulsification"

07/06/2019

Anissa Nofita Sari, Doctoral course student in Disease Mechanism
Supervisor: Prof. Renu Wadhwa KAUL

English Presentation Award

The award was presneted to the student for her presentation at 92nd annual meeting of the Japanese Tissue Culture Association (JTCA). This conference was held during July 6-7, 2019 at The Nippon Dental University, Tokyo, Japan.

25/03/2019

Kazuyuki Sakamoto, Doctoral course Graduate in Drug Discovery
Supervisor: Prof. Sosuke Miyoshi

Presidents Award

The award was presneted to the student for his academic and research performance during his PhD course. This felicitation was held during the University graduation ceremony held on March 25, 2019 at University of Tsukuba, Tsukuba.

01/03/2019

Sekove Vodo, Doctoral course student in Food Innovation
Supervisor: Prof. Marcos Antonio Das NEVES

Best Poster Award

The award was presneted to the student for his poster presentation at 22nd Euro-Global summit on Food & Beverages. This conference was held during February 28- March 01, 2019 at London, UK.

"Valorization of sugarcane bagasse as an emulsifier in O/W emulsion by hydrothermal liquefaction (HTL) pre-treatment"

08/11/2018

Meriem Bejaoui, Doctoral students in Drug Discovery
Supervisor: Prof. Hiroko Isoda

Excellent Oral Presentation

The award was presneted to the students for their oral presentations at 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2018). This conference was held during November 5-8, 2018 at Tsukuba, Japan.

"Elucidation of Hair Growth and Hair Pigmentation Promotion Effect of 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)"

08/11/2018

Munkzul Ganbold, Doctoral students in Drug Discovery
Supervisor: Prof. Hiroko Isoda

Excellent Oral Presentation

The award was presneted to the students for their oral presentations at 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2018). This conference was held during November 5-8, 2018 at Tsukuba, Japan.

"Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis"

18/10/2018

Nurul Syahirah Shamsol Anuar, Doctoral students in Environmental Management
Supervisor: Prof. Iwane Suzuki

Best Presentation Award

The award was presented to the student for her research presentation at 17th World Lake Conference. This was held during October 14-19, 2018 at Tsukuba international congress center, Tsukuba, Japan.

"Genomic analysis of two odoriferous Streptomyces Sp. isolated from tropical freshwater of southeast Asia provides an insight into the identification of potential temperature sensor"

20/09/2018

Muhammad Gilang Ramadhan, Master course student in Food Innovation
Supervisor: Prof. Mitsutoshi Nakajima

Best Poster Award

The award was presneted to the student for his poster presentation titled "Efficient water removal from Water-in-Oil Emulsions by High Electric Field Demulsification", at 50th Society Chemical Engineering Japan (SCEJ) Autumn Meeting. This conference was held during September 18-20, 2018 at Kagoshima University, Japan.

05/07/2018

Atsushi TSUYUKUBO, Master course student in Drug Discovery
Prof. Toshiyuki Kanamori

ISMM Award

18/04/2018

Nanda Yuli Rahmawati, Master course student in Disease Mechanism
Supervisor: Prof. Yasuhiro Yasutomi

Best poster Award

The award was presneted to the student for her poster presentation titled "Characterization of Human Parainfluenza Type 2 Virus Containing Ag85B as a Novel TB Vaccine Candidate", at "International Conference on Vaccine & Immunology". This conference was held during April 16-18, 2018 at Tokyo, Japan.

21/09/2017

Muhammad Gilang Ramadhan, Master course student in Food Innovation
Supervisor: Prof. Mitsutoshi Nakajima

Best Poster Award

The award was presneted to the student for his poster presentation titled "Water removal of W/O Model Emulsions of Microalgae Bio-crude Oil using Electrostatic Demulsification", at " 49th Society Chemical Engineering Japan (SCEJ) Autumn Meeting. This conference was held during September 20-22, 2017 at Nagoya University, Japan.

14/04/2017

Gaofeng Shu, Doctral course student in Food Innovation
Supervisor: Prof. Mitsutoshi Nakajima

Tsukuba Scholarship

14/04/2017

Gaofeng Shu, Doctral course student in Food Innovation
Supervisor: Prof. Mitsutoshi Nakajima

Overseas Academic Conference Participation Support Program