Master's/Doctoral Program in Life Science Innovation

Kuniya Abe

Team Leader HP
Technology and Development Team for Mammalian Genome Dynamics, RIKEN BRC

Professor, School of Integrative and Global Majors, University of Tsukuba

Research field: Developmental Genetics

1. Development, differentiation and epigenetics of mammalian pluripotent cells and germ cells
2. Developmental genetics of mammalian early embryogenesis
3. Development and characterization of novel pluripotent stem cells in human and mice
4. Development of cellular phenotyping technology based on image processing and machine learning

Selected Publications:

1. "Xist/Tsix expression dynamics during mouse peri-implantation development revealed by whole-mount 3D RNA-FISH", Scientific Reports 2019, 9 (1), 3637.
2. "A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition", Stem Cell Reports 2015, 4 (4), 744-757.
3. "Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions", Cell Reports 2012, 2 (5), 1363-1374.

Renu Wadhwa iD researchmap

Laboratory Leader HP
DAILAB, Biomedical Research Institute, AIST

Professor, School of Integrative and Global Majors, University of Tsukuba

Research field: Biology of Cellular Aging, Cancer and Stress

1. Molecular mechanism of cellular senescence, tumorigenesis and anti-aging
2. Anti-cancer and anti-aging properties of traditional Indian medicine, Ayurveda
3. Mortalin Biology: cellular stress, senescence, tumorigenesis and in vivo imaging

Selected Publications:

1. "Molecular Insights Into Withaferin-A-Induced Senescence: Bioinformatics and Experimental Evidence to the Role of NFκB and CARF", The Journals of Gerontology: Series A 2018, 74 (2), 183-191.
2. "Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence", Journal of Experimental & Clinical Cancer Research 2019, 38 (1), 103.
3. "CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target", Oncogenesis 2018, 7 (5), 39.

Masashi Yanagisawa TRIOS researchmap

Director and Professor HP
International Institute for Integrative Sleep Medicine, University of Tsukuba

Research field: Neuroscience of Sleep

1. Large-scale, forward genetic screening of genes responsible for sleep/wake regulation in mice
2. Discovery and medicinal chemistry of novel drugs for sleep disorders
3. Visualizing and manipulating the activity of neurons involved in sleep/wake regulation

Selected Publications:

1. "Quantitative phosphoproteomic analysis of the molecular substrates of sleep need", Nature 2018, 558 (7710), 435-439.
2. "Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models", Proceedings of the National Academy of Sciences of the United States of America 2017, 114 (22), 5731-5736.
3. "Forward-genetics analysis of sleep in randomly mutagenized mice", Nature 2016, 539 (7629), 378-383.

Yasuhiro Yasutomi researchmap

Director HP
Tsukuba Primate Research Center, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Atsushi Yoshiki iD

Head HP
Experimental Animal Division, RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Bioresource Science for Laboratory Mouse

1. Collection, preservation, quality-control and distribution of mouse resources
2. Research and development for quality control of mouse resources
3. Development of novel tools for gene functions and mouse models for human diseases

Selected Publications:

1. "Off- and on-target effects of genome editing in mouse embryos", Journal of Reproduction and Development 2019, 65 (1), 1-5.
2. "Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality", Neurobiology of Disease 2016, 96, 271-283.
3. "High-throughput discovery of novel developmental phenotypes", Nature 2016, 537, 508–514.

Katsutaka OishiiD researchmap

Research Group Leader HP
Biological Clock Research Group, Biomedical Research Institute,AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

Tomoko Kuwabara iD

Senior Researcher HP
Stem Cell Engineering Research Group,
Biotechnology Research Institute for Drug Discover, AIST

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Regulatory Analysis of Adult Stem Cells

1. Adult neurogenesis in mammalian brain
2. Activation of adult stem cells
3. Environmental effects on adult stem cells and the changes under diseases

Selected Publications:

1. "Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis", The FASEB Journal 2011, 25 (10), 3570-3582.
2. "Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb", EMBO Molecular Medicine 2011, 3 (12), 742-754.
3. "Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis", Nature Neuroscience 2009, 12 (9), 1097-1105.

Yohei HayashiiD

Team Leader HP
iPS Cell Advanced Characterization and Development Team, RIKEN BRC

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Stem Cell Biology, Regenerative Medicine, iPS cells

1. Disease modeling and drug development using disease (patient)-specific iPS cells
2. Studying and improving iPS cell reprogramming
3. Development of novel technologies of cell culture, cell handling, and cell analysis

Selected Publications:

1. "Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells", Nature 2014, 507, 99-103.
2. "Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells", PNAS 2015, 112(15), 4666-4671.
3. "BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence", PNAS 2016, 113(46), 13057-13062.

Dong-Zhu Xu TRIOS researchmap

Course Coordinator of T-LSI (Disease Mechanism Course)

Associate Professor
Faculty of Medicine, University of Tsukuba

Sosaku Ichikawa iD TRIOS researchmap

Professor
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Functional Carrier Design and Engineering

1. Development and characterization of emulsion-based carrier systems
2. Development and characterization of liposome-based carrier systems
3. Development of new nano-/micro- carrier systems for efficient delivery of bioactive

Selected Publications:

1. "Freeze-dryable lipid vesicles with size tunability and high encapsulation efficiency prepared by the multiple emulsification-solvent evaporation method", Colloids and Surfaces B: Biointerfaces 2017, 159, 412-418.
2. "Mixing characterization of liquid contents in human gastric digestion simulator equipped with gastric secretion and emptying", Biochemical Engineering Journal 2017, 122, 85-90.
3. "Development and Fundamental Characteristics of a Human Gastric Digestion Simulator for Analysis of Food Disintegration", Japan Agricultural Research Quarterly: JARQ 2017, 51 (1), 17-25.

Hiroko Isoda iD TRIOS researchmap

Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Toshikazu Kamiya

Research Fellow
Kyowa Hakko Bio Co., Ltd.

Professor, School of Integrative and Global Majors,
University of Tsukuba
*New students will not be recruited in 2021.

Toshiyuki Kanamori

Team Leader HP
Drug Assay Device Research Group,
Biotechnology Research Institute for Drug Discovery, AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Transport Phenomena in biomedical system

1. Transport Phenomena in biomedical system
2. Mathematical modeling for biomedical system
3. Biomedical application of functional polymer

Selected Publications:

1. "Fabrication of pocket-like hydrogel microstructures through photolithography", Soft Matter 2018, 14 (28), 5710-5714.
2. "Technical aspects of microphysiological systems (MPS) as a promising wet human- in-vivo simulator", Drug Metabolism and Pharmacokinetics 2018, 33 (1), 40-42.
3. "Morphology-based optical separation of subpopulations from a heterogeneous murine breast cancer cell line", PLOS ONE 2017, 12 (6), e0179372.

Ken-ichi Tominaga iD

Deputy Director
Laboratory for Food and Medicinal Resource Engineering (FoodMed-OIL), AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

Takashi Arimura iD

Invited Research Scholar
AIST・Univ. of Tsukuba Open Innovation Laboratory for Food and Medical Resource Engineering, AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

1. Functionalization and development of plant resources
2. Creation of allosteric systems in response to external stimuli
3. Molecular Robotics: Gellular particles that self-assemble and communicate with one another, realizing cellular automata

Selected Publications:

1. "Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects", BioMed Research International 2020, 2020, 9584567.
2. "Electrochemically Switchable Molecular-Tweezers", Journal of Oleo Science 2017, 66 (4), 419-423.
3. "A Belousov–Zhabotinsky Oscillator Driven by a Water‐Soluble Metalloporphyrin", Chemistry Select 2016, 1 (4), 877-878.

Hiroshi Nagase iD researchmap

Specially Appointed Professor HP
International Institute for Integrative Sleep Medicine, University of Tsukuba

Noriki Kutsumura iD TRIOS researchmap

Tetsuya Sakurai iD TRIOS researchmap

Director HP
Center for Artificial Intelligence Research, University of Tsukuba

Professor, Faculty of Engineering, Information and Systems, University of Tsukuba

Research field: Computational Algorithms

1. Mathematical methods for data analysis
2. High performance algorithms on large-scale scientific simulations
3. Eigenvalue analysis

Selected Publications:

1. "Distributed collaborative feature selection based on intermediate representation", Proceedings of the 28th International Joint Conference on Artificial Intelligence (IJCAI-19) 2019, accepted.
2. "Complex moment-based supervised eigenmap for dimensionality reduction", Proceedings of the Thirty-Third AAAI Conference on Artificial Intelligence (AAAI-19) 2019, accepted.
3. "Spectral feature scaling method for supervised dimensionality reduction", Proceedings of the 27th International Joint Conference on Artificial Intelligence (IJCAI-18) 2018, 2560-2566.

Shinji Sugiura iD researchmap

Chief Senior Researcher HP
Drug Assay Device Research Group,
Biotechnology Research Institute for Drug Discovery, AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Biochemical Engineering

1. Organs-on-a-chip for drug discovery
2. Engineering the micro-scale cell culture environment
3. Micro-scale cell process engineering with functional materials

Selected Publications:

1. "A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform", Lab on a Chip 2018, 18 (1), 115-125.
2. "Morphology-based optical separation of subpopulations from a heterogeneous murine breast cancer cell line", PLOS ONE 2017, 12 (6), e0179372.
3. "Click-crosslinkable and photodegradable gelatin hydrogels for cytocompatible optical cell manipulation in natural environment", Scientific Reports 2015, 5 (1), 15060.

Makoto Miyagishi iD researchmap

Group Leader HP
Molecular Composite medicine Research Group,
Biomedical Research Institute, AIST

Professor, School of Integrative and Global Majors,
University of Tsukuba

Hiroyuki Ito iD

Director
Astellas Pharma Inc.

Professor, School of Integrative and Global Majors,
University of Tsukuba

Tsunenori Kameda iD researchmap

Unit Leader HP
Silk Materials Research Unit, Division of Biotechnology,
Institute of Agrobiological Sciences, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Silk Materials Research

1. Fundamental reserch on relation between the structure and properties of silk proteins
2. Development of various fabrication processes for formation of innovative silk materials with different characteristics
3. Commercialize the various unutilized silk produced by insects other than silkworm as new material.

Selected Publications:

1. "A study of the extraordinarily strong and tough silk produced by bagworms", Nature Communications 2019, 10 (1), 1469.
2. "Transdermal delivery of 40-nm silk fibroin nanoparticles", Colloids and Surfaces B: Biointerfaces 2019, 175, 564-568.
3. "Genome Editing Advances the Structural Study of Silk", ACS Biomaterials Science & Engineering 2018, 4 (3), 832-835.

Naohiro NodaiD

Group Leader HP
Bio-analytical Research Group, Biomedical Research Institute, AIST

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Yusaku Miyamae iD TRIOS researchmap

Course Coordinator of T-LSI (Drug Discovery Course)

Associate Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Chemical Biology

1. Development of screening system for identification of new bioactive small molecules and mechanism of action
2. Rational design and synthesis of new bioactive substances
3. Development of new chemical genetic tools for control of cellular protein stability

Selected Publications:

1. "Importance of the Proximity and Orientation of Ligand-Linkage to the Design of Cinnamate-GW9662 Hybrid Compounds as Covalent PPARγ Agonists", Molecules 2019, 24 (10), 2019.
2. "Tetrandrine induces lipid accumulation through blockade of autophagy in a hepatic stellate cell line", Biochemical and Biophysical Research Communications 2016, 477 (1), 40-46.
3. "Identification of a New Type of Covalent PPARγ Agonist using a Ligand-Linking Strategy", ACS Chemical Biology 2015, 10 (12), 2794-2804.

Hiroko Isoda iD TRIOS researchmap

Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Toshikazu Kamiya

Research Fellow
Kyowa Hakko Bio Co., Ltd.

Professor, School of Integrative and Global Majors,
University of Tsukuba
*New students will not be recruited in 2021.

Susumu Kawasaki researchmap

Senior Researcher HP
Food Research Institute, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

Isao Kobayashi iD researchmap

Principal Researcher HP
Food Research Institute, NARO

Professor, School of Integrative and Global Majors,
University of Tsukuba

Masatomo Kobayashi

Head HP
Experimental Plant Division, RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Kunihiko Uemura

Laboratory Head HP
Food Research Institute, NARO

Kenichi Kashiwagi iD TRIOS researchmap

Associate Professor HP
Faculty of Humanities and Social Sciences, University of Tsukuba

Research field: Development Economics, Economy of Middle East and North Africa

1. Mechanism of productivity and technological progress in agro-food industry
2. Analysis on develoment of agro-food clusters based on promotion of local industries
3. Analysis on innovative agro-food value chain

Selected Publications:

1. "Technical Efficiency of Olive-growing Farms in the Northern West Bank of Palestine", Sustainable Agriculture Research 2017, 6(1), 125-140.
2. "Technical efficiency of olive oil firms under the industrial upgrading programme in Tunisia", New Medit: A Mediterranean Journal of Economics, Agriculture and Environment 2016, 15(4), 10-20.
3. "Productivity Growth and Technological Progress in the Palestinian Economy: Empirical Evidence from the West Bank", Advances in Management & Applied Economics 2016, 6(1), 69-88.

Marcos Antonio Das NEVES iD TRIOS

Associate Professor researchmap HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Food Engineering

1. Food nanotechnology
2. Development of functional foods
3. Food emulsions as bioactives delivery systems

Selected Publications:

1. "Assessment of Oxidative Stability in Fish Oil-in-Water Emulsions: Effect of Emulsification Process, Droplet Size and Storage Temperature", Journal of Food Process Engineering 2015, 40 (1), e12316.
2. "Antimicrobial Oil-in-Water Nanoemulsions: Synergistic Effect of Nisin and Carvacrol against Bacillus subtilis", Journal of Food Science and Engineering 2016, 6 (2), 63-74.
3. "Development of novel bioactives delivery systems by micro/nanotechnology", Current Opinion in Food Science 2015, 1, 7-12.

Kazuichi Sakamoto TRIOS researchmap

Associate Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Nutrigenomics

1. Longevity genes and bioactive stimulus
2. Bioactive stimulus for anti-lifestyle related diseases
3. Bioactive stimulus for anti-aging

Selected Publications:

1. "Soy sauce increased the oxidative stress tolerance of nematode via p38 MAPK pathway", Bioscience, Biotechnology, and Biochemistry 2019, 83 (4), 709-716.
2. "Killed Bifidobacterium longum enhanced stress tolerance and prolonged life span of Caenorhabditis elegans via DAF-16", British Journal of Nutrition 2018, 120 (8), 872-880.
3. "Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes", Bioscience, Biotechnology, and Biochemistry 2018, 83 (1), 148-154.

Satoshi Fukumitsu

Nippon Flour Mills. Co., Ltd. Innovation center Manager

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Myra O. Villareal iD TRIOS researchmap

Course Coordinator of T-LSI (Food Innovation Course)

Associate Professor
Faculty of Life and Environmental Sciences, University of Tsukuba

Mitsuko Aono researchmap

Dupty director HP
Center for Environmental Biology and Ecosystem, NIES

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Mechanism of stress response in Plants

1. Molecular-biological studies on effect of tropospheric ozone and other stress factors on plants in global environmental changes
2. Dynamics of genetically-modified crops in the wild

Selected Publications:

1. "Ozone-Sensitive Arabidopsis Mutants with Deficiencies in Photorespiratory Enzymes", Plant and Cell Physiology 2017, 58 (5), 914-924.
2. "Seeds of a Possible Natural Hybrid between Herbicide-Resistant Brassica napus and Brassica rapa Detected on a Riverbank in Japan", GM Crops 2011, 2 (3), 201-210.
3. "Disruption of a Gene Encoding C4-Dicarboxylate Transporter-Like Protein Increases Ozone Sensitivity Through Deregulation of the Stomatal Response in Arabidopsis thaliana", Plant and Cell Physiology 2008, 49 (1), 2-10.

Hiroyuki Fuchino researchmap

Head HP
Research Center for Medicinal Plant Resources, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Hirofumi Hara iD

Associate Professor HP
Department of Chemical Process Engineering, Malaysia-Japan International Institute of Technology (MJIIT), Universiti Teknologi Malaysia

Associate Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: The tropics environmental microbiology

1. Investigation of microbial diversity in the various environments of tropical area
2. Characterization and application of tropical microorganisms for the conversion of unutilized biomass
3. Bioremediation of environmental pollutants in tropical area by regional microbes

Selected Publications:

1. "Microbial Diversity in Decaying Oil Palm Empty Fruit Bunches (OPEFB) and Isolation of Lignin-degrading Bacteria from a Tropical Environment", Microbes and Environments 2019, 34 (2), 161-168.
2. "Whole gene transcriptomic analysis of PCB/biphenyl degrading Rhodococcus jostii RHA1", The Journal of General and Applied Microbiology, in press.
3. "Depolymerization of lignocellulose of oil palm empty fruit bunch by thermophilic microorganisms from tropical climate", Bioresource Technology 2019, 279, 174-180.

Masanobu Kawachi iD

Head HP
Biodiversity Resource Conservation Section, Center for Environmental Biology and Ecosystem Studies, NIES

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Algal Resources, Algal Biodiversity

1. Isolation, culturing and preservation of algal resources
2. Utilization of algal resources
3. Biodiversity and taxonomy of algal resources

Selected Publications:

1. "Identification of 13 Spirogyra species (Zygnemataceae) by traits of sexual reproduction induced under laboratory culture conditions", Scientific Reports 2019, 9 (1), 7458.
2. "Raphidocelis subcapitata (=Pseudokirchneriella subcapitata) provides an insight into genome evolution and environmental adaptations in the Sphaeropleales", Scientific Reports 2018, 8 (1), 8058.
3. "Application of cryopreservation to genetic analyses of a photosynthetic picoeukaryote community", Gene 2016, 576 (2), 708-716.

Masanori KikuchiiD researchmap

Group leader HP
Bioceramics Group, NIMS

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Bioceramics

1. Ceramics in medicine
2. Application of bio-derived minerals
3. Biomimetic materials

Selected Publications:

1. "Preparation of anti-decay self-setting pastes of hydroxyapatite/collagen utilizing (3-glycidoxypropyl)trimethoxysilane", Journal of Asian Ceramic Societies 2018, 6 (4), 322-331.
2. "Reactivity Improvement of Dicalcium Phosphate Dihydrate with Fluoride for Its Removal from Waste and Drinking Water", Universal Journal of Materials Science 2016, 4 (3), 60-64.
3. "Self-organization mechanism in a bone-like hydroxyapatite/collagen nanocomposite synthesized in vitro and its biological reaction in vivo", Biomaterials 2001, 22 (13), 1705-1711.

Masatomo Kobayashi

Head HP
Experimental Plant Division,
RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Moriya Ohkuma

Head HP
Microbe Division (Japan Collection of Microorganisms),
RIKEN BRC

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Microbial Resources and Diversity

1. Genomics and bioresources of yet-uncultured microbial diversity
2. Molecular microbial ecology of microbial symbionts
3. Taxonomy and systematics of diverse microorganisms

Selected Publications:

1. "Isolation and characterization of a thermophilic sulfur- and iron-reducing thaumarchaeote from a terrestrial acidic hot spring", The ISME Journal, in press.
2. "Lactococcus reticulitermitis sp. nov., isolated from the gut of the subterranean termite Reticulitermes speratus", International Journal of Systematic and Evolutionary Microbiology 2018, 68 (2), 596-601.
3. "Acetogenesis from H2plus CO2and nitrogen fixation by an endosymbiotic spirochete of a termite-gut cellulolytic protist", Proceedings of the National Academy of Sciences 2015, 112 (33), 10224-10230.

Iwane Suzuki iD TRIOS researchmap

Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Functional Regulation of Photosynthesis

1. Interaction of carbon and nitrogen metabolism in microalgae
2. Mechanisms for acclimation to environmental conditions of photosynthetic activity
3. Biochemical and molecular biological studies in biomass production in microalgae

Selected Publications:

1. "Cold-regulated genes under control of the cold sensor Hik33 in Synechocystis", Molecular Microbiology 2001, 40 (1), 235-244.
2. "The pathway for perception and transduction of low-temperature signals in Synechocystis", The EMBO Journal 2000, 19 (6), 1327-1334.
3. "Genetic engineering of the unsaturation of fatty acids in membrane lipids alters the tolerance of Synechocystis to salt stress", Proceedings of the National Academy of Sciences 1999, 96 (10), 5862-5867.

Kenji Tamura TRIOS researchmap

Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Research field: Soil Environmental Chemistry

1. Analysis of soil microelements
2. Mechanism of High quality soils

Selected Publications:

1. "Interregional traceability of Tunisian olive oils to the provenance soil by multielemental fingerprinting and chemometrics", Food Chemistry 2019, 283, 656-664.
2. "Six-year monitoring of the vertical distribution of radiocesium in three forest soils after the Fukushima Dai-ichi Nuclear Power Plant accident", Journal of Environmental Radioactivity 2018, 192, 172-180.
3. "Physiological and Psychological Effects of Scent of Soil on Human Beings", Open Journal of Soil Science 2017, 07 (09), 235-244.

Tomoya Tsuji iD

Professor HP
Malaysia-Japan International Institute of Technology (MJIIT), Universiti Teknologi Malaysia

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Thermodynamics for Chemical Engineering

1. Phase Equilibrium for the system containing spray propellant
2. Measurement and prefiction of solubility of inorganic gases in organic compounds
3. Therimophysical properties of dimethyl ether

Selected Publications:

1. "Measurement and prediction of bubble point pressure of a novel solvent with propellant for color spray", Fluid Phase Equilibria 2020, 505, 112366.
2. "Gas solubilities of nitrogen or oxygen in benzene, divinylbenzene, styrene and of an equimolar (N2:O2) mixture in styrene at (293–313) K", Fluid Phase Equilibria, 2019, 492, 34-40.
3. "SO2 Solubility in Low Molecular Weight Polyethylene Glycol Dimethyl Ether and Correlation using Cubic Equation of State", Journal of Solution Chemistry 2019, 48, 1035-1045.

Kayo Yoshimatsu researchmap

Head HP
Research Center for Medicinal Plant Resources, NIBIOHN

Professor, School of Integrative and Global Majors,
University of Tsukuba

Takeshi Nakayama TRIOS researchmap

Associate Professor HP
Faculty of Life and Environmental Sciences, University of Tsukuba

Ryozo Noguchi TRIOS

Associate Professor
Faculty of Life and Environmental Sciences,
University of Tsukuba

Research field: Bio-resource Process and System Engineering (Agricultural Machinery Lab.)

1. System Analysis for microalgae oil production
2. Rice Husk Combustion Control for Material and Energy Utilization

Selected Publications:

1. <"Engineering Study of a Pilot Scale Process Plant for Microalgae-Oil Production Utilizing Municipal Wastewater and Flue Gases: Fukushima Pilot Plant", Energies 2018, 11 (7), 1693.
2. "Comparative environmental impact evaluation of palm oil mill effluent treatment using a life cycle assessment approach: A case study based on composting and a combination for biogas technologies in North Sumatera of Indonesia", Journal of Cleaner Production 2018, 184, 1028-1040.
3. "Microalgae Oil Production: A Downstream Approach to Energy Requirements for the Minamisoma Pilot Plant", Energies 2018, 11 (3), 521.

Zhongfang Lei iD TRIOS researchmap

Associate Professor
University of Tsukuba Faculty of Life and Environmental Sciences

Shinya Takahashi iD TRIOS researchmap

Course Coordinator of T-LSI (Environmental Management Course)

Assistant Professor
Faculty of Life and Environmental Sciences, University of Tsukuba

Tetsuya Sakurai iD TRIOS researchmap

Director HP
Center for Artificial Intelligence Research,
University of Tsukuba

Professor, Faculty of Engineering, Information and Systems,
University of Tsukuba

Research field: Computational Algorithms

1. Mathematical methods for data analysis
2. High performance algorithms on large-scale scientific simulations
3. Eigenvalue analysis

Selected Publications:

1. "Distributed collaborative feature selection based on intermediate representation", Proceedings of the 28th International Joint Conference on Artificial Intelligence (IJCAI-19) 2019, accepted.
2. "Complex moment-based supervised eigenmap for dimensionality reduction", Proceedings of the Thirty-Third AAAI Conference on Artificial Intelligence (AAAI-19) 2019, accepted.
3. "Spectral feature scaling method for supervised dimensionality reduction", Proceedings of the 27th International Joint Conference on Artificial Intelligence (IJCAI-18) 2018, 2560-2566.

Hiroki Shiroi

Executive fellow
Modality Research Labs., Astellas Pharma Inc.

Professor, School of Integrative and Global Majors,
University of Tsukuba

Tsuyoshi Miyazaki iD researchmap

MANA Principal Investigator/Group Leader HP
International Center for Materials Nanoarchitectonics
NIMS

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Electronic Structure Calculation

1. First-principles calculation
2. Molecular simulation
3. Computional Materials Science

Selected Publications:

1. "Efficient Calculation of Electronic Structure Using O(N) Density Functional Theory", Journal of Chemical Theory and Computation 2017, 13 (9), 4146-4153.
2. "Density-functional theory study of gramicidin A ion channel geometry and electronic properties", Journal of The Royal Society Interface 2013, 10 (89), 20130547.
3. "O(N) methods in electronic structure calculations", Reports on Progress in Physics 2012, 75 (3), 036503.

Itoshi Nikaido iD researchmap

Team Leader HP
Laboratory for Bioinformatics Research,
RIKEN Center for Biosystems Dynamics Research

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Genome Science, Bioinformatics

1. A development of novel bioinforamtics techniques for genome science

Selected Publications:

1. "CellFishing.jl: an ultrafast and scalable cell search method for single-cell RNA sequencing", Genome Biology 2019, 20 (1), 31.
2. "Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads", Genome Biology 2018, 19 (1), 29.
3. "Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs", Nature Communications 2018, 9 (1), 619.

Hiroshi Masuya iD researchmap

Head HP
Integrated Bioresource Information Division,
RIKEN BioResource Research Center

Professor, School of Integrative and Global Majors,
University of Tsukuba

Research field: Bioinformatics and data integration

1. Data integration and standardization of bioresouce-related information
2. Development of homepage contents for communication tool for bioresouce-related information
3. Development of methodology of the big-data analysis and data visualization

Selected Publications:

1. "An atlas of evidence-based phenotypic associations across the mouse phenome.", Sci. Rep. 2020, 10, 3957.
2. "RIKEN MetaDatabase: A Database Platform for Health Care and Life Sciences as a Microcosm of Linked Open Data Cloud.", Int. J. Semantic Web Inf. Syst. 2018, 14(1), 140-164.
3. "Identification of genetic elements in metabolism by high-throughput mouse phenotyping.", Nat. Commun. 2018, 9, 288.

Ranjith Kumar Bakku iD TRIOS

Course Coordinator of T-LSI (Bioinformatics Course)

Assistant Professor
Faculty of Engineering, Information and Systems,University of Tsukuba

Research field: Multi-Omics integration and Gene-regulatory interactions

1. Development of Metabolic-Regulatory-Maps (MRM) for Precision medicine studies
2. Plant transcriptomics and gene-regulatory analysis
3. Environmental and Micro Algal studies

Selected Publications:

1. "Promising Polyunsaturated Oils from Marine Haptophyta", Journal of Ecology & Natural Resources 2018, 2 (5), 000143.
2. "Changes in the accumulation of alkenones and lipids under nitrogen limitation and its relation to other energy storage metabolites in the haptophyte alga Emiliania huxleyi CCMP 2090", Journal of Applied Phycology 2017, 30 (1), 23-36.
3. "Expression of Genes for a Flavin Adenine Dinucleotide-Binding Oxidoreductase and a Methyltransferase from Mycobacterium chlorophenolicum Is Necessary for Biosynthesis of 10-Methyl Stearic Acid from Oleic Acid in Escherichia coli", Frontiers in Microbiology 2017, 8, 2061.